We use a combination of computer simulations, statistical mechanics and modeling, to study the structure, function, folding, and dynamics of proteins in solution. Current research projects include problems in the statistical mechanics of solutions, protein folding and ligand binding, and protein dynamics on longer time scales. We are interested in the interplay between computational models and experiments at different levels of spatial and temporal resolution from atomic to mesoscopic, and from femtoseconds to seconds. Together with a group of investigators with complementary expertise in molecular biology, statistical physics, control theory, and computer science, we are working to develop computational models for complex biological systems involved in the regulation of gene expression.

Our current research activities include: Developing implicit solvent models Replica Exchange Molecular Dynamics Multi-scale modeling and Distance-restrained docking of biological assemblies Ligand binding and Conformational equilibria of biomolecules Modeling protein folding pathways For in-depth project descriptions, see our Research Page or Publication List.

Ronald M. Levy Department of Chemistry & Chemical Biology Rutgers, The State University of New Jersey 610 Taylor Road Piscataway, NJ 08854 Phone: 732-445-3947 Fax: 732-445-5958 email: ronlevy@lutece.rutgers.edu

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Last updated: November 2005